Potential of notochordal cells within injectable biomaterials to promote intervertebral disc regeneration

Low back pain is the leading cause of disability worldwide and is strongly associated with degeneration of the intervertebral disc (IVD). During degeneration the nucleus pulposus (NP) in the core of the IVD, is affected by altered matrix synthesis, increased degradation, and cell loss. Strategies co...

Full description

Bibliographic Details

Published in:	European Cells & Materials
Main Authors:	RJ Williams, S Basatvat, TC Schmitz, R Janani, C Sammon, K Benz, K Ito, MA Tryfonidou, JW Snuggs, CL Le Maitre
Format:	Article
Language:	English
Published:	Forum Multimedia Publishing LLC 2024-03-01
Subjects:	ivd degeneration disc degeneration biomaterial notochordal cells hydrogels hyaluronic acid
Online Access:	https://www.ecmjournal.org/papers/vol047/vol047a03.php