Gut microbiome signatures predict 5-ASA efficacy in ulcerative colitis

Summary: Ulcerative colitis (UC) prevalence is rising globally, yet fewer than 50% of patients achieve mucosal healing (MH) with first-line 5-aminosalicylic acid (5-ASA) therapy. We aimed to identify microbial signatures that could predict the treatment efficacy of 5-ASA. Active UC patients on stand...

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Bibliographic Details
Published in:iScience
Main Authors: Yan Dang, Xinyi Xu, Jiuyue Ma, Minsi Zhou, Chenyue Xu, Xueping Huang, Fang Xu, Zhan Wang, Haiyun Shi, Shutian Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Subjects:
Health sciences
Gastroenterology
Microbiology
Microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008296

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http://www.sciencedirect.com/science/article/pii/S2589004225008296

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