Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mitochondrial disruption

Abstract Gastric cancer is highly lethal due to late-stage diagnosis and resistance to standard treatments like radiotherapy. Enhancing radiosensitivity in gastric cancer cells could improve treatment outcomes. Withaferin A (WA), a bioactive compound from Withania somnifera, has anticancer effects a...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Ping Lu, Juan Xue, Xuemeng JI
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Subjects:
Withaferin A
Autophagy
Radiotherapy
Gastric cancer
Radiosensitizer
Online Access:https://doi.org/10.1038/s41598-025-05008-x

Internet

https://doi.org/10.1038/s41598-025-05008-x

Similar Items