Severe Acute Respiratory Syndrome Coronavirus 2 Receptor (Human Angiotensin-Converting Enzyme 2) Binding Inhibition Assay: A Rapid, High-Throughput Assay Useful for Vaccine Immunogenicity Evaluation

Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show immune evasion of vaccine-derived immunity, highlighting the need for better clinical immunogenicity biomarkers. To address this need, an enzyme-linked immunosorbent assay-based, human angiotensin-converting enzym...

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Bibliographic Details

Published in:	Microorganisms
Main Authors:	Joyce S. Plested, Mingzhu Zhu, Shane Cloney-Clark, Edmond Massuda, Urvashi Patel, Andrew Klindworth, Michael J. Massare, Rongman Cai, Louis Fries, Greg Glenn, Raj Kalkeri
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	COVID-19 human angiotensin-converting enzyme 2 (hACE2) immunogenicity SARS-CoV-2 assay validation neutralizing antibody titers
Online Access:	https://www.mdpi.com/2076-2607/11/2/368