iPiDA-LGE: a local and global graph ensemble learning framework for identifying piRNA-disease associations

Abstract Background Exploring piRNA-disease associations can help discover candidate diagnostic or prognostic biomarkers and therapeutic targets. Several computational methods have been presented for identifying associations between piRNAs and diseases. However, the existing methods encounter challe...

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Bibliographic Details

Published in:	BMC Biology
Main Authors:	Hang Wei, Jialu Hou, Yumeng Liu, Alexey K. Shaytan, Bin Liu, Hao Wu
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	piRNA-disease association identification Graph ensemble learning Local context graph
Online Access:	https://doi.org/10.1186/s12915-025-02221-y