Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin

The transient receptor potential vanilloid 1 (TRPV1) ion channel is a member of the family of Transient Receptor Potential (TRP) channels that acts as a molecular detector of noxious signals in primary sensory neurons. Activated by capsaicin, heat, voltage and protons, it is also well known for its...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Yorley Duarte, Javier Cáceres, Romina V. Sepúlveda, Diego Arriagada, Pedro Olivares, Ignacio Díaz-Franulic, Jimmy Stehberg, Fernando González-Nilo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-07-01
Subjects:	transient receptor potential vanilloid 1 channels TRPV1 drug discovery capsaicin analgesic carrageenan
Online Access:	https://www.frontiersin.org/article/10.3389/fphar.2020.01040/full