Design, Synthesis, and Preliminary Antiproliferative Evaluation of 1,2,4-Thiadiazole Derivatives as Possible Histone Deacetylase Inhibitors
Histone deacetylases (HDACs) are a class of proteins that responsible of the hydrolysis of N-acetyl lysine residues in histones as well as non-histone protein substrates. This phenomenon may provide an explanation for the involvement of these enzymes in a wide range of clinical situations, encompas...
| Published in: | Iraqi Journal of Pharmaceutical Sciences |
|---|---|
| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy University of Baghdad
2025-02-01
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| Subjects: | |
| Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/3548 |