Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

Abstract Background It is unclear whether plant-derived extracellular vesicles (EVs) can mediate interspecies communication with mammalian cells. Tumor-associated macrophages (TAMs) display a continuum of different polarization states between tumoricidal M1 phenotype and tumor-supportive M2 phenotyp...

Full description

Bibliographic Details

Published in:	Journal for ImmunoTherapy of Cancer
Main Authors:	Meng Cao, Huaijiang Yan, Xuan Han, Ling Weng, Qin Wei, Xiaoyan Sun, Wuguang Lu, Qingyun Wei, Juan Ye, Xueting Cai, Chunping Hu, Xiaoyang Yin, Peng Cao
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2019-11-01
Subjects:	Extracellular vesicles (EVs) Ginseng-derived nanoparticles Tumor-associated macrophages (TAM) Macrophage polarization Melanoma
Online Access:	http://link.springer.com/article/10.1186/s40425-019-0817-4