Membrane-Binding Mechanism of Clostridium perfringens Alpha-Toxin

Clostridium perfringens alpha-toxin is a key mediator of gas gangrene, which is a life-threatening infection that manifests as fever, pain, edema, myonecrosis, and gas production. Alpha-toxin possesses phospholipase C and sphingomyelinase activities. The toxin is composed of an N-terminal domain (1–...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Toxins
المؤلفون الرئيسيون: Masataka Oda, Yutaka Terao, Jun Sakurai, Masahiro Nagahama
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2015-12-01
الموضوعات:
Clostridium perfringens
alpha-toxin
C-domain
central loop domain
phospholipid
ganglioside GM1a
TrkA
endocytosis
vaccine
الوصول للمادة أونلاين:http://www.mdpi.com/2072-6651/7/12/4880

الانترنت

http://www.mdpi.com/2072-6651/7/12/4880

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