Characterization of hydrophobic peptides in the presence of detergent by photoionization mass spectrometry.
The characterization of membrane proteins is still challenging. The major issue is the high hydrophobicity of membrane proteins that necessitates the use of detergents for their extraction and solubilization. The very poor compatibility of mass spectrometry with detergents remains a tremendous obsta...
| Published in: | PLoS ONE |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Online Access: | http://europepmc.org/articles/PMC3827311?pdf=render |