Activatable Sulfur Dioxide Nanosonosensitizer Enables Precisely Controllable Sono‐Gaseous Checkpoint Trimodal Therapy for Orthotopic Hepatocellular Carcinoma

Abstract Immune checkpoint blockade (ICB) is combined with sonodynamic therapy (SDT) to increase response rates and enhance anticancer efficacy. However, the “always on” property of most sonosensitizers in reducing tumor microenvironment (TME) compromises the therapeutic outcome of sonoimmunotherapy...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Jing Liang, Guangwen Cheng, Luping Qiu, Liyun Xue, Huning Xu, Xiaohui Qiao, Na Guo, Huijing Xiang, Yu Chen, Hong Ding
Format:	Article
Language:	English
Published:	Wiley 2025-02-01
Subjects:	gas therapy immunotherapy nanomedicine nanosonosensitizer sonodynamic therapy
Online Access:	https://doi.org/10.1002/advs.202409442