Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.

Increasing evidence points to defects in autophagy as a common denominator in most neurodegenerative conditions. Progressive functional decline in the autophagy-lysosomal pathway (ALP) occurs with age, and the consequent impairment in protein processing capacity has been associated with a higher ris...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Carmela Matrone, Nicolas Dzamko, Peder Madsen, Mette Nyegaard, Regina Pohlmann, Rikke V Søndergaard, Louise B Lassen, Thomas L Andresen, Glenda M Halliday, Poul Henning Jensen, Morten S Nielsen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Online Access:	http://europepmc.org/articles/PMC4979956?pdf=render