Possible Enantioseparation of Racemic Ribose on Chiral Surface Formed by Adsorption of Nucleobases

The paper proposes a putative prebiotic scenario leading to homochirality in the RNA world. In this scenario, racemic ribose, the only chiral moiety in RNA, was enantioseparated (in its pyranose form) on a chiral surface formed by the adsorption of (prochiral) nucleobases (NBs) on a mineral or metal...

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Bibliographic Details

Published in:	Life
Main Authors:	Roman Bielski, Michal Tencer
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	enantioseparation nucleobases chiral surface enantiopure ribose formation absolute enantioselective separation
Online Access:	https://www.mdpi.com/2075-1729/15/8/1160