Single-cell RNA-seq reveals the communications between extracellular matrix-related components and Schwann cells contributing to the earlobe keloid formation

Keloid is a major type of skin fibrotic disease, with one prominent feature of extensive accumulation of extracellular matrix (ECM) components, and another feature of pain/itching, which is closely related to the peripheral nervous system (PNS). However, the molecular pathogenesis of these two promi...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Taogen Gong, Yayu Wang, Shaowei Dong, Xiaoshi Ma, Danfeng Du, Chang Zou, Qijun Zheng, Zhong Wen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	scRNA-seq earlobe keloid Schwann cells ECM-related populations cell interactions site-specific pathogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2022.1000324/full