Boosting CAR-T cell therapy with CRISPR technology

Chimeric antigen receptor (CAR)-T cell therapy has made remarkable breakthroughs in treating cancers, especially hematologic malignancies, yet its broader application in cancer treatment is hindered by multiple challenges. Meanwhile, the development of clustered regularly interspaced short palindrom...

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Bibliographic Details
Published in:hLife
Main Authors: Liyanran Yan, Shanzi Gao, Xinhui Wang, Xintao Zhou, Praopim Limsakul, Yiqian Wu
Format: Article
Language:English
Published: Elsevier 2024-08-01
Subjects:
chimeric antigen receptor (CAR)-T cell therapy
clustered regularly interspaced short palindromic repeats (CRISPR)
immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2949928324000488

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http://www.sciencedirect.com/science/article/pii/S2949928324000488

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