miRNA‐221 and miRNA‐222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours

Aberrantly expressed microRNAs (miRNAs) are involved in many diseases including cancer. In gastrointestinal stromal tumours (GISTs) expression of miR‐221 and miR‐222 is reduced compared to control tissue and other sarcomas but the functional effects of this downregulation are not fully understood. T...

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Bibliographic Details

Published in:	Molecular Oncology
Main Authors:	Michaela Angelika Ihle, Marcel Trautmann, Helen Kuenstlinger, Sebastian Huss, Carina Heydt, Jana Fassunke, Eva Wardelmann, Sebastian Bauer, Hans-Ulrich Schildhaus, Reinhard Buettner, Sabine Merkelbach-Bruse
Format:	Article
Language:	English
Published:	Wiley 2015-08-01
Subjects:	miR-221 miR-222 GIST KIT Expression Apoptosis
Online Access:	https://doi.org/10.1016/j.molonc.2015.03.013