In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization.

The aberrant expression of aldo keto reductases (AKR1B1 & AKR1B10) has been extensively studied in different types of cancer especially the colon cancer but a very few studies have yet been reported regarding the discovery of inhibitors for the treatment of colon cancer by targeting these isozym...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	PLoS ONE
المؤلفون الرئيسيون:	Syeda Abida Ejaz, Amna Saeed, Pervez Rashid Birmani, Khadijah Mohammedsalaeh Katubi, Zainab Mufarreh Elqahtani, M S Al-Buriahi, Rabail Ujan, Farhan Siddique, Samia Ben Ahmed, Z A Alrowaili
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2022-01-01
الوصول للمادة أونلاين:	https://doi.org/10.1371/journal.pone.0271602