LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry

Abstract Insertion of lipopolysaccharide (LPS) into the bacterial outer membrane (OM) is mediated by a druggable OM translocon consisting of a β-barrel membrane protein, LptD, and a lipoprotein, LptE. The β-barrel assembly machinery (BAM) assembles LptD together with LptE at the OM. In the enterobac...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Yiying Yang, Haoxiang Chen, Robin A. Corey, Violette Morales, Yves Quentin, Carine Froment, Anne Caumont-Sarcos, Cécile Albenne, Odile Burlet-Schiltz, David Ranava, Phillip J. Stansfeld, Julien Marcoux, Raffaele Ieva
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Online Access:https://doi.org/10.1038/s41467-023-42007-w