Molecular and Evolution <i>In Silico</i> Studies Unlock the h4-HPPD C-Terminal Tail Gating Mechanism

The enzyme 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) is involved in the catabolism of the amino acid tyrosine in organisms such as bacteria, plants, and animals. It catalyzes the conversion of 4-hydroxyphenylpyruvate to a homogenisate in the presence of molecular oxygen and Fe(II) as a cofactor....

全面介紹

書目詳細資料

發表在:	Biomedicines
Main Authors:	Alfonso Trezza, Ancuta Birgauan, Michela Geminiani, Anna Visibelli, Annalisa Santucci
格式:	Article
語言:	英语
出版:	MDPI AG 2024-05-01
主題:	4-HPPD gating mutagenesis C-terminal tail molecular modeling molecular dynamics simulations
在線閱讀:	https://www.mdpi.com/2227-9059/12/6/1196