The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

Abstract Decline in cognitive function is the most feared aspect of ageing. Poorer midlife cognitive function is associated with increased dementia and stroke risk. The mechanisms underlying variation in cognitive function are uncertain. Here, we assessed associations between 1160 proteins’ plasma l...

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Bibliographic Details

Published in:	Translational Psychiatry
Main Authors:	Rosie M. Walker, Michael Chong, Nicolas Perrot, Marie Pigeyre, Danni A. Gadd, Aleks Stolicyn, Liu Shi, Archie Campbell, Xueyi Shen, Heather C. Whalley, Alejo Nevado-Holgado, Andrew M. McIntosh, Stefan Heitmeier, Sumathy Rangarajan, Martin O’Donnell, Eric E. Smith, Salim Yusuf, William N. Whiteley, Guillaume Paré
Format:	Article
Language:	English
Published:	Nature Publishing Group 2024-05-01
Online Access:	https://doi.org/10.1038/s41398-024-02915-x