Geniposide alleviates lipopolysaccharide-caused apoptosis of murine kidney podocytes by activating Ras/Raf/MEK/ERK-mediated cell autophagy

Proteinuria is one of the most important clinical features of nephrotic syndrome (NS). Injury of podocyte has been proved to contribute to the occurrence of proteinuria. This study explored the effects of geniposide (GEN) on lipopolysaccharide (LPS)-caused murine kidney podocyte MPC5 apoptosis and a...

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Bibliographic Details
Published in:Artificial Cells, Nanomedicine, and Biotechnology
Main Authors: Xia Li, Aijing Ma, Kun Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Subjects:
Nephrotic syndrome
podocytes
geniposide
cell apoptosis
cell autophagy
Ras/Raf/MEK/ERK pathway
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1601630

Internet

https://www.tandfonline.com/doi/10.1080/21691401.2019.1601630

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