A simple geometrical model of the electrostatic environment around the catalytic center of the ribosome and its significance for the elongation cycle kinetics

The central function of the large subunit of the ribosome is to catalyze peptide bond formation. This biochemical reaction is conducted at the peptidyl transferase center (PTC). Experimental evidence shows that the catalytic activity is affected by the electrostatic environment around the peptidyl t...

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Bibliographic Details

Published in:	Computational and Structural Biotechnology Journal
Main Authors:	Marc Joiret, Frederic Kerff, Francesca Rapino, Pierre Close, Liesbet Geris
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2001037023002568