LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

IntroductionThe association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with the clinical outcome after allogeneic transplantation (alloHSCT) has been described. Lymphocyte Activation 3 (LAG3) is a surface protein that plays a regulatory role in immunity as...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	David Cruz, Rocío Rodríguez-Romanos, Marta González-Bartulos, Irene García-Cadenas, Rafael de la Cámara, Inmaculada Heras, Ismael Buño, Nazly Santos, Natàlia Lloveras, Pilar Velarde, Esperanza Tuset, Carmen Martínez, Marcos González, Guillermo F. Sanz, Christelle Ferrá, Antonia Sampol, Rosa Coll, Jose A. Pérez-Simón, Javier López-Jiménez, Manuel Jurado, David Gallardo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	LAG3: lymphocyte activation gene 3 graft-versus-host disease allogeneic transplant immune response checkpoint molecules
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1066393/full