Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection

Background. U65, a self-aggregating peptide scaffold, traps fused protein antigens in yeast cells. Conversion to Yeast Cell Particle (YCP) vaccines by partial removal of surface mannoproteins exposes β-glucan, mediating efficient uptake by antigen-presenting cells (APCs). YCP vaccines are inexpensiv...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Journal of Immunology Research
المؤلفون الرئيسيون: Donald J. Tipper, Eva Szomolanyi-Tsuda
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2016-01-01
الوصول للمادة أونلاين:http://dx.doi.org/10.1155/2016/2743292