FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate

BackgroundThe beneficial effects of fibroblast growth factor 21 (FGF21) and sodium butyrate (NaB) on protection against cholestasis-induced liver fibrosis are not well known. This study aimed to explore the effects of FGF21 and NaB on bile duct ligation (BDL)-induced liver fibrosis.MethodsWild-type...

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Bibliographic Details
Published in:Frontiers in Pharmacology
Main Authors: Jing Yang, Lei Chen, Shan-Shan Zhao, Chuang Du, Yi-Zhe Fan, Hui-Xin Liu, Yongchun Li, Yong-Zhi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Subjects:
FGF21
cholestasis
liver fibrosis
sodium butyrate
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1422770/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1422770/full

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