Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation

Summary: Mitochondria are multifaceted organelles crucial for cellular homeostasis that contain their own genome. Mitochondrial DNA (mtDNA) replication is a spatially regulated process essential for the maintenance of mitochondrial function, its defect causing mitochondrial diseases. mtDNA replicati...

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Bibliographic Details
Published in:iScience
Main Authors: Hema Saranya Ilamathi, Sara Benhammouda, Amel Lounas, Khalid Al-Naemi, Justine Desrochers-Goyette, Matthew A. Lines, François J. Richard, Jackie Vogel, Marc Germain
Format: Article
Language:English
Published: Elsevier 2023-07-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012579