Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells

Background & Aims: Liver diseases resulting from chronic HBV infection are a significant cause of morbidity and mortality. Vaccines that elicit T-cell responses capable of controlling the virus represent a treatment strategy with potential for long-term effects. Here, we evaluated vaccines t...

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Bibliographic Details

Published in:	JHEP Reports
Main Authors:	Anna H. Mooney, Sarah L. Draper, Olivia K. Burn, Regan J. Anderson, Benjamin J. Compton, Chingwen Tang, Kathryn J. Farrand, Pietro Di Lucia, Micol Ravà, Valeria Fumagalli, Leonardo Giustini, Elisa Bono, Dale I. Godfrey, William R. Heath, Weiming Yuan, Francis V. Chisari, Luca G. Guidotti, Matteo Iannacone, John Sidney, Alessandro Sette, Shivali A. Gulab, Gavin F. Painter, Ian F. Hermans
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Subjects:	Hepatitis B virus Glycolipid peptide conjugate vaccine Natural killer T cells Synthetic long peptide
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589555924000399