Age at menarche, age at natural menopause, and risk of rheumatoid arthritis — a Mendelian randomization study

Abstract Background Hormonal reproductive factors have been suggested to play an important role in the etiology of rheumatoid arthritis (RA), an autoimmune inflammatory disorder affecting primarily women. We conducted a two-sample Mendelian randomization (MR) study examining three relevant exposures...

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Bibliographic Details

Published in:	Arthritis Research & Therapy
Main Authors:	Jingjing Zhu, Zheng Niu, Lars Alfredsson, Lars Klareskog, Leonid Padyukov, Xia Jiang
Format:	Article
Language:	English
Published:	BMC 2021-04-01
Subjects:	Mendelian randomization Rheumatoid arthritis Age at menarche Age at natural menopause Age at first birth
Online Access:	https://doi.org/10.1186/s13075-021-02495-x