Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions

Abstract Metabolic coupling of Mycobacterium tuberculosis to its host is foundational to its pathogenesis. Computational genome‐scale metabolic models have shown utility in integrating ‐omic as well as physiologic data for systemic, mechanistic analysis of metabolism. To date, integrative analysis o...

Full description

Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Aarash Bordbar, Nathan E Lewis, Jan Schellenberger, Bernhard Ø Palsson, Neema Jamshidi
Format:	Article
Language:	English
Published:	Springer Nature 2010-10-01
Subjects:	computational biology host‐pathogen Mycobacterium tuberculosis systems biology macrophage
Online Access:	https://doi.org/10.1038/msb.2010.68