Breaking the feed forward inflammatory cytokine loop in the tumor microenvironment of PDGFB-driven glioblastomas
Glioblastoma (GBM) tumor-associated macrophages (TAMs) provide a major immune cell population contributing to growth and immunosuppression via the production of proinflammatory factors, including IL-1. In this issue of the JCI, Chen, Giotti, and colleagues investigated loss of ll1b in the immune tum...
| Published in: | The Journal of Clinical Investigation |
|---|---|
| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2023-11-01
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| Online Access: | https://doi.org/10.1172/JCI175127 |