Monocyte Infiltration and Differentiation in 3D Multicellular Spheroid Cancer Models

Tumor-associated macrophages often correlate with tumor progression, and therapies targeting immune cells in tumors have emerged as promising treatments. To select effective therapies, we established an in vitro 3D multicellular spheroid model including cancer cells, fibroblasts, and monocytes. We a...

Full description

Bibliographic Details

Published in:	Pathogens
Main Authors:	Natasha Helleberg Madsen, Boye Schnack Nielsen, Son Ly Nhat, Søren Skov, Monika Gad, Jesper Larsen
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Subjects:	3D cancer cell models multicellular spheroids tumor-associated macrophages tumor microenvironment drug screening in vitro assay
Online Access:	https://www.mdpi.com/2076-0817/10/8/969