Recombinant infectious bronchitis virus containing mutations in non-structural proteins 10, 14, 15, and 16 and within the macrodomain provides complete protection against homologous challenge

ABSTRACT Infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute highly contagious economically important disease of chickens. Vaccination uses live attenuated vaccines (LAVs) that are generated via serial passage of a virulent field isolate through embryonated...

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Bibliographic Details

Published in:	Journal of Virology
Main Authors:	Sarah Keep, Katalin Foldes, Guilia Dowgier, Graham Freimanis, Chandana Tennakoon, Shafiyeel Chowdhury, Adam Rayment, James Kirk, Trinity Bakshi, Phoebe Stevenson-Leggett, Yana Chen, Paul Britton, Erica Bickerton
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-04-01
Subjects:	infectious bronchitis virus vaccine macrodomain coronavirus avian Mac1
Online Access:	https://journals.asm.org/doi/10.1128/jvi.01663-24