Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment

Glioblastoma (GBM) is the most common and devastating primary brain tumor, leading to a uniform fatality after diagnosis. A major difficulty in eradicating GBM is the presence of microscopic residual infiltrating disease remaining after multimodality treatment. Glioma cancer stem cells (CSCs) have b...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Henry Ruiz-Garcia, Keila Alvarado-Estrada, Paula Schiapparelli, Alfredo Quinones-Hinojosa, Daniel M. Trifiletti
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Subjects:	glioma tumor microenvironment stem cell bioprinting organoids organ-on-a-chip
Online Access:	https://www.frontiersin.org/article/10.3389/fncel.2020.558381/full