Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice

Regulatory T (Treg) cells are essential for maternal immune tolerance of the fetus and placenta. In preeclampsia, aberrant Treg cell tolerance is implicated, but how Treg cells affect the uterine vascular dysfunction thought to precede placental impairment and maternal vasculopathy is unclear. We us...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Shanna L. Hosking, Lachlan M. Moldenhauer, Ha M. Tran, Hon Y. Chan, Holly M. Groome, Evangeline A.K. Lovell, Ella S. Green, Stephanie E. O’Hara, Claire T. Roberts, Kerrie L. Foyle, Sandra T. Davidge, Sarah A. Robertson, Alison S. Care
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2025-01-01
Subjects:	Immunology Reproductive biology
Online Access:	https://doi.org/10.1172/jci.insight.169836