The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies

Abstract Mass spectrometry-based targeted proteomics allows objective protein quantitation of clinical biomarkers from a single section of formalin-fixed, paraffin-embedded (FFPE) tumor tissue biopsies. We combined high-field asymmetric waveform ion mobility spectrometry (FAIMS) and parallel reactio...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Steve Sweet, David Chain, Wen Yu, Philip Martin, Marlon Rebelatto, Andrew Chambers, Fabiola Cecchi, Yeoun Jin Kim
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Online Access:	https://doi.org/10.1038/s41598-022-16358-1