Nanoliposomal Irinotecan in Combination With 5‐Fluorouracil and Leucovorin for Advanced Head and Neck and Esophageal Squamous Cell Carcinoma After Prior Platinum‐Based Chemotherapy or Chemoradiotherapy: A Multicenter Phase II Trial

ABSTRACT Purpose To evaluate the efficacy and safety of nanoliposomal irinotecan (nal‐IRI) plus 5‐fluorouracil (5‐FU) and leucovorin (LV) in patients with platinum‐refractory or intolerant head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC). Methods In this mu...

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Bibliographic Details

Published in:	Cancer Medicine
Main Authors:	Muh‐Hwa Yang, Shang‐Yin Wu, I‐Wei Ho, Nai‐Jung Chiang, Chin‐Fu Hsaio, Chen‐Yuan Lin, Ming‐Yu Lien, Peter Mu‐Hsin Chang, Jia‐Hong Chen, Ching‐Yun Hsieh, Ruey‐Long Hong, Chao‐Tung Lee, Li‐Tzong Chen, Tsang‐Wu Liu, Chang‐Fang Chiu, Li‐Yuan Bai
Format:	Article
Language:	English
Published:	Wiley 2025-10-01
Subjects:	esophageal cancer head and neck cancer nanoliposomal irinotecan platinum squamous cell carcinoma
Online Access:	https://doi.org/10.1002/cam4.71307