Biphasic effects of α-asarone on immobility in the tail suspension test: Evidence for the involvement of the noradrenergic and serotonergic systems in its antidepressant-like activity

Alpha (α)-asarone is one of the main psychoactive compounds, present in Acorus species. Evidence suggests that the α-asarone possess an antidepressant-like activity in mice. However, the exact dose-dependent effect of α-asarone and mechanism(s) involved in the antidepressant-like activity are not cl...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Chellian eRanjith kumar, Vijayapandi ePandy, Zahurin eMohamed
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-03-01
Subjects:	Depression Prazosin Yohimbine PcpA AMPT WAY100635
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00072/full