Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma

Background The deregulation of several transcription factors contribute to the aggressive course of mantle cell lymphoma. This study focuses on survival signals emanating from the tumor environment and involving the signal transducer and activator of transcription (STAT) 3 through cytokines or antig...

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Bibliographic Details
Published in:Haematologica
Main Authors: Fanny Baran-Marszak, Mohand Boukhiar, Stéphanie Harel, Christelle Laguillier, Claudine Roger, Remy Gressin, Antoine Martin, Remi Fagard, Nadine Varin-Blank, Florence Ajchenbaum-Cymbalista, Dominique Ledoux
Format: Article
Language:English
Published: Ferrata Storti Foundation 2010-11-01
Online Access:https://haematologica.org/article/view/5782