The iSEARCH randomised controlled trial protocol: a pragmatic Australian phase III clinical trial of intrapartum sildenafil citrate to improve outcomes potentially related to intrapartum hypoxia

Introduction We showed in a phase II randomised controlled trial (RCT) that oral sildenafil citrate in term labour halved operative birth for fetal distress. We outline the protocol for a phase III RCT (can intrapartum SildEnafil safely Avert the Risks of Contraction-induced Hypoxia? (iSEARCH)) of 3...

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Ben W Mol, Vicki Flenady, Sailesh Kumar, Emily Callander, William Tarnow-Mordi, Nadia Badawi, Susan P Walker, Helen Liley, R O'Connell, Lene Seidler, Jonathan Hyett
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2024-09-01
Online Access:	https://bmjopen.bmj.com/content/14/9/e082943.full