Retinoic acid-related orphan receptor γ (RORγ): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity.

The hepatic circadian clock plays a key role in the daily regulation of glucose metabolism, but the precise molecular mechanisms that coordinate these two biological processes are not fully understood. In this study, we identify a novel connection between the regulation of RORγ by the clock machiner...

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Bibliographic Details
Published in:PLoS Genetics
Main Authors: Yukimasa Takeda, Hong Soon Kang, Johannes Freudenberg, Laura M DeGraff, Raja Jothi, Anton M Jetten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Online Access:https://doi.org/10.1371/journal.pgen.1004331