HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance

Abstract Background Pseudouridine synthase (PUS) 7 is a member of the PUS family that catalyses pseudouridine formation. It has been shown to be involved in intellectual development and haematological malignancies. Nevertheless, the role and the underlying molecular mechanisms of PUS7 in solid tumou...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Dan Song, Ming Guo, Shuai Xu, Xiaotian Song, Bin Bai, Zhengyan Li, Jie Chen, Yanxin An, Yongzhan Nie, Kaichun Wu, Shiqi Wang, Qingchuan Zhao
Format:	Article
Language:	English
Published:	BMC 2021-05-01
Subjects:	Colorectal cancer Metastasis PUS7 HSP90 LASP1
Online Access:	https://doi.org/10.1186/s13046-021-01951-5