Enhancement of NETosis by ACE2-cross-reactive anti-SARS-CoV-2 RBD antibodies in patients with COVID-19

Abstract Background High levels of neutrophil extracellular trap (NET) formation or NETosis and autoantibodies are related to poor prognosis and disease severity of COVID-19 patients. Human angiotensin-converting enzyme 2 (ACE2) cross-reactive anti-severe acute respiratory syndrome coronavirus 2 spi...

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Bibliographic Details

Published in:	Journal of Biomedical Science
Main Authors:	Kun-Han Hsieh, Chiao-Hsuan Chao, Yi-Ling Cheng, Yen-Chung Lai, Yung-Chun Chuang, Jen-Ren Wang, Sui-Yuan Chang, Yuan-Pin Hung, Yi-Ming Arthur Chen, Wei-Lun Liu, Woei-Jer Chuang, Trai-Ming Yeh
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	COVID-19 Anti-ACE2 autoantibody NETosis Cross-reactivity Thrombosis
Online Access:	https://doi.org/10.1186/s12929-024-01026-5