Heart rate responses to a muscarinic agonist in rats with experimentally induced acute and subacute chagasic myocarditis

We administered arecoline to rats, with experimentally induced chagasic myocarditis, in order to study the sinus node sensitivity to a muscarinic agonist. Sixteen month old rats were inoculated with 200,000 T. cruzi parasites ("Y" strain). Between days 18 and 21 (acute stage), 8 infected r...

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Bibliographic Details

Published in:	Revista do Instituto de Medicina Tropical de São Paulo
Main Authors:	Argenis TORRES, Diego F. DÁVILA, Carlos F. GOTTBERG, Jose H. DONIS, Gabriela ARATA DE BELLABARBA, Paolo RAMONI-PERAZZI
Format:	Article
Language:	English
Published:	Universidade de São Paulo (USP) 2000-08-01
Subjects:	Arecoline Chagas´ disease Muscarinic agonist Muscarinic receptor T. cruzi Parasympathetic
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652000000400007&tlng=en