Elevation of gangliosides in four brain regions from Parkinson’s disease patients with a GBA mutation

Abstract A number of genetic risk factors have been identified over the past decade for Parkinson’s Disease (PD), with variants in GBA prominent among them. GBA encodes the lysosomal enzyme that degrades the glycosphingolipid, glucosylceramide (GlcCer), with the activity of this enzyme defective in...

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Bibliographic Details

Published in:	npj Parkinson's Disease
Main Authors:	Shani Blumenreich, Tamar Nehushtan, Or B. Barav, Jennifer T. Saville, Tamir Dingjan, John Hardy, Maria Fuller, Anthony H. Futerman
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Online Access:	https://doi.org/10.1038/s41531-022-00363-2