Molecular mechanisms of lipid droplets-mitochondria coupling in obesity and metabolic syndrome: insights and pharmacological implications

Abnormal lipid accumulation is a fundamental contributor to obesity and metabolic disorders. Lipid droplets (LDs) and mitochondria (MT) serve as organelle chaperones in lipid metabolism and energy balance. LDs play a crucial role in lipid storage and mobilization, working in conjunction with MT to r...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Chunmei Zhang, Mingxuan Zheng, Runlin Bai, Jiale Chen, Hong Yang, Gan Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	lipid droplets mitochondria peridroplet mitochondria obesity metabolic syndrome pharmacotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1491815/full