The desmosomal cadherin Desmoglein-2 controls extracellular matrix expression and remodeling via NF-κB signaling in keratinocytes

Desmogleins are transmembrane cadherin proteins and obligate members of the desmosome, a cell-cell adhesion complex which connects adjacent cells and provides structural integrity to tissues. While Desmogleins are well-known for their importance in maintenance of cell-cell junctions, several studies...

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الحاوية / القاعدة:	Frontiers in Cell and Developmental Biology
المؤلفون الرئيسيون:	Sadie E. Hunter, Zara T. Patel, Beatriz Mateo, Joshua M. Powers, Austin Y. Shull, Adi D. Dubash
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2025-10-01
الموضوعات:	desmoglein 2 desmosome cadherin extracellular matrix (ECM) keratinocyte wound healing
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1691260/full