High resolution mapping of enhancer-promoter interactions.

RNA Polymerase II ChIA-PET data has revealed enhancers that are active in a profiled cell type and the genes that the enhancers regulate through chromatin interactions. The most commonly used computational method for analyzing ChIA-PET data, the ChIA-PET Tool, discovers interaction anchors at a spat...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Christopher Reeder, Michael Closser, Huay Mei Poh, Kuljeet Sandhu, Hynek Wichterle, David Gifford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:http://europepmc.org/articles/PMC4430501?pdf=render