RETRACTED ARTICLE: LATS2 overexpression attenuates the therapeutic resistance of liver cancer HepG2 cells to sorafenib-mediated death via inhibiting the AMPK–Mfn2 signaling pathway

Abstract Background Effective therapy for hepatocellular carcinoma (HCC) is currently an imperative issue, and sorafenib is a first-line drug for the treatment of HCC. However, the clinical benefit of sorafenib is often impaired by drug resistance. Accordingly, the present study was conducted to inv...

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Bibliographic Details
Published in:Cancer Cell International
Main Authors: Jie Song, Wei Zhao, Chang Lu, Xue Shao
Format: Article
Language:English
Published: BMC 2019-03-01
Subjects:
HCC
Mitophagy
Sorafenib
AMPK pathway
LATS2
Online Access:http://link.springer.com/article/10.1186/s12935-019-0778-1

Internet

http://link.springer.com/article/10.1186/s12935-019-0778-1

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