GABA_A and GABA_B Receptors Mediate GABA-Induced Intracellular Ca²⁺ Signals in Human Brain Microvascular Endothelial Cells

Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABA_A receptors on cerebrovascular endothelial cells, whereas the endothelial...

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Bibliographic Details

Published in:	Cells
Main Authors:	Sharon Negri, Francesca Scolari, Mauro Vismara, Valentina Brunetti, Pawan Faris, Giulia Terribile, Giulio Sancini, Roberto Berra-Romani, Francesco Moccia
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	hCMEC/D3 cells GABA GABA<sub>A</sub> receptors GABA<sub>B</sub> receptors Ca<sup>2+</sup> signaling InsP<sub>3</sub> receptors
Online Access:	https://www.mdpi.com/2073-4409/11/23/3860