Acryl-3,5-bis(2,4-difluorobenzylidene)-4-piperidone targeting cellular JUN proto-oncogene, AP-1 transcription factor subunit inhibits head and neck squamous cell carcinoma progression

Aim: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with a survival rate below fifty percent. Addressing meager therapeutic options, a series of small molecule inhibitors were screened for antitumor efficacy. The most potent analog, acryl-3,5-bis(2,4-difluo...

Full description

Bibliographic Details

Published in:	Exploration of Targeted Anti-tumor Therapy
Main Authors:	Levi Arnold, Juan Pineda Gomez, Michael Barry, Marrion Yap, Laura Jackson, Thuc Ly, David Standing, Subhash B. Padhye, Bernhard Biersack, Shrikant Anant, Sufi Mary Thomas
Format:	Article
Language:	English
Published:	Open Exploration Publishing Inc. 2023-10-01
Subjects:	head and neck squamous cell carcinoma jun proto-oncogene transcription factor small molecule inhibitor
Online Access:	https://www.explorationpub.com/Journals/etat/Article/1002184